Compatible with Windows 7

MedCalc update history

Version 11.2.1 - February 5, 2010

Added optional reference lines in all graphs.
Added MedCalc version number in prints of datasheet and results.
Added date and time in prints of datasheet.

Version 11.2 - January 23, 2010

New in Reference Interval estimation:
- an option to test for outliers
- Box-Cox power transformation
- a graph option
Added an option for a 2.5-97.5 percentile error bar in different graphs.
Changed the formula for the confidence interval of the hazard ratio in Kaplan-Meier survival analysis (Armitage et al., 2002).
Fixed a minor bug in the variables list that occurred after editing duplicate column headers.
Fixed a bug in Multiple Comparison graphs where labels on the X-axis were converted to uppercase.
Changed the formula for the P-value for the Mann-Whitney test (resulting in a different P-value when the number is ties is high).
Change in the algorithm for Trimmed mean (the calculated number of cases to trim is now rounded to the closest integer, in previous versions it was truncated).

Version 11.1 - October 7, 2009

In ROC curve analysis, added the DeLong method (1988) for calculating the Standard Error of the Area Under the Curve (AUC), and of the difference between two AUCs.
Added an option to calculate the Confidence Interval for the Area Under the Curve (AUC) as AUC ± 1.96 SE (Standard Error).
Added Time-weighted average and Left-align time option in Serial measurements.
Added 95% Confidence Interval for Rates and Comparison of two rates.
Renamed the "Line" (for means or medians) graph type option into "Connecting Line" and added a new graph type option "Horizontal line" in Data comparison graphs, Multiple comparison graphs, Clustered multiple comparison graphs, Multiple variables graphs and Clustered multiple variables graphs.
Redesigned dialog boxes for statistical and graphical procedures with a Data panel on the left and an Options panel on the right side.
Data comparison graphs now have editable text on the vertical axis (but no title).
Variable name is now the default text on the Y-axis in Multiple comparison graphs and Clustered multiple comparison graphs.
Fixed a problem with the marker style for mean or median in the Data comparison graphs.
Corrected a bug in the conversion of time data when importing Excel files.
Corrected a bug in Multiple Variables graphs where extreme values sometimes were not correctly displayed in box-and-whisker plots.

Version 11.0.1 - September 1, 2009

Fixed a bug in the Statistical spreadsheet functions on variables (VAVERAGE etc.) that could occur in some instances when sample size is 0.
Fixed a bug that caused the Logistic regression procedure to fail in some circumstances.

Version 11 - August 3, 2009

Windows 7 compatibility.
Revised icons and toolbars.
Faster start-up time.
Improved high DPI support (high resolutions screens).
Shortened start-up time and increased responsiveness.
Merged Format spreadsheet and Format column dialog boxes.
Added 95% CI for linear regression coefficients.
Many other minor revisions and improvements.

Version 10.4 - April 24, 2009

Revised reference interval with inclusion of the "robust method" as described in the CLSI Guidelines C28-A3.
Added Friedman test.
Added Intraclass correlation coefficient.

Version 10.1 - February 15, 2009

Added analysis of covariance (ANCOVA).
2-way analysis of variance has been completely revised.
Repeated measures analysis of variance: added Greenhouse-Geisser and Huynh-Feldt corrections for non-sphericity.

Version 10 - November 17, 2008

New: auto-update feature, Repeated measures analysis of variance, a new a post-hoc test for the Kruskal-Wallis test.
Movable and editable legend boxes in all graphs.
Revised Normal plot and histogram.
Full screen view mode.
Improved copy/Paste functionality.

Version 9.6 - July, 1 2008

Added several new options in the Bland & Altman plot.
Options to calculate Confidence Intervals for Likelihood ratios and Predictive values in Roc curve analysis.
Added ROC curve analysis (calculation of the AUC, or c-statistic) as a tool for model evaluation in Logistic regression, see Logistic regression.
Rearranged the Options dialog box, with several new options, including an option to show/hide the splash screen at program startup.

Version 9.5 - April 12, 2008

In the Format column dialog box, a default value or formula can be specified for spreadsheet columns. This value or formula is applied to all cells in the column that otherwise would be empty. Default values are displayed in a different color, which can be selected in the Format spreadsheet box.
Go to cell: go directly to any cell in the spreadsheet.
Added a formula bar in the spreadsheet window.
Added a "Paste values" command in the spreadsheet context menu (this is the menu which appears when you right-click in the spreadsheet window).
Added statistical spreadsheet functions on variables.

Version 9.4 - January 16, 2008

Calculate interval-specific likelihood ratios from raw data (Statistics menu) or from data summarized in a 2xk table (Tests menu).
Multiple line graph: Creates a graph that shows consecutive observations of different variables.
Diagnostic test (2x2 table)
Option to calculate a Trimmed Mean in Summary Statistics.
Added an option in the Find and Find & replace procedures: Match entire cell contents. Unselect this option to enable in-cell find & replace.

Version 9.3 - November 5, 2007

Support new Excel 2007 file formats *.xlsx and *.xlsm.

Version 9.2 - November 8, 2006

Full compatibility with the upcoming new Windows version "Vista".
Test for one proportion.
Comparison of the Areas under two independent ROC curves.
Data transformations: Rank cases, Percentile ranks, z-scores.
Click-through commands: below statistical results, click-through commands (presented as browser links) are available.
Different graph commands in results window for Summary statistics, Correlation, Rank correlation, Regression, T-test, ANOVA, etc.
Print and Help buttons inside the results windows.
Spreadsheet formatting: text effects such as bold, italic and underline can now be applied to columns, rows, or ranges of cells.

Version 9 - July 9, 2006

Redesigned user-interface.
Improved the quality of graphs.
New layout for text reports.
Added several new tools for generating random samples, categorizing continuous variables, and randomization. See Tools menu.
New in method comparison: Concordance correlation coefficient command (Statistics menu)
New Create summary statistics table command (Statistics menu)
New Create correlation table command (Statistics menu)

Version 8.2 - February 21, 2006

Added Levene's Test for Equality of Variances in ANOVA.
Increased the number of variables and independent variables from 6 to 24 for multiple regression, logistic regression, Cox proportional-hazards regression, multiple variables graph and clustered variables graph.
In all graph plots, the (x,y) values corresponding with the mouse position in the graph, are displayed in the status bar.
Added a graph option to have the tickmarks displayed on the outside of the graph frame. See Format graph.
Added log transformation option for Plot versus criterion values graph and Interactive dot plot (ROC curve analysis graphs).

Version 8.1 - June 14, 2005

New in ROC curve analysis: a new graph that allows to plot sensitivity and specificity (optionally with 95% Confidence Interval) versus criterion values.
95% Confidence Bounds (Hilgers, 1991) for the ROC curve.
Added a P-value for the Area under the Curve in ROC curve analysis (null hypothesis: Area under ROC curve = 0.5).
Added the Independent samples t-test with correction for unequal variances (Welch test).
Several changes in the graphical subsystem.
Improved general performance.

Version 8 - March 4, 2005

Improved international support and better support for Windows' Accessibility Options such as High Contrast.
Added sample size calculations for ROC curve analysis and comparison of ROC curves.

Version 7.6 - January 3, 2005

One sample t-test, Signed rank sum test.

Version 7.5 - November 9, 2004

Added statistical analysis of Serial measurements.